|
KMID : 1143120210110030027
|
|
Asia Pacific Allergy
2021 Volume.11 No. 3 p.27 ~ p.27
|
|
|
Successful treatment of a patient with adult food allergy and severe asthma using omalizumab
|
|
Nishie Miyuki
Masaki Katsunori
Okuzumi Shinichi
Mochimaru Takao
Kabata Hiroki
Miyata Jun
Takahashi Hayato
Fukunaga Koichi
|
|
|
Abstract
|
|
|
|
Food allergy is a typical immediate-onset allergic disease in which symptoms are provoked by exposure to the sensitized antigens. Although previous reports have shown that omalizumab has helped children with egg or milk allergy achieve oral immunotherapy safely, there is still no established method for induction of remission in adult food allergy. A 51-year-old woman with oral steroid-dependent severe asthma was treated with omalizumab for 6 years. She had shellfish and wheat food allergy and oral allergy syndrome induced by kiwi and other foods associated with latex-fruit syndrome. Since omalizumab treatment, her food allergy symptoms had disappeared. After 7 years of this treatment, disseminated erythema suddenly appeared; omalizumab was discontinued because of suspected drug-induced eruption. After omalizumab interruption, she felt an itching sensation in her throat with worsened asthma control immediately after wheat ingestion. Readministration of omalizumab improved these symptoms. Thus, we raised the possibility that omalizumab not only improved asthma control but also induced pharmacological remission of the patient's food allergy. Omalizumab may be considered as a treatment option for adult patients with food allergies and severe asthma.
|
|
|
KEYWORD
|
|
|
Omalizumab, Food allergy, Oral allergy syndrome, Latex-fruit syndrome, Asthma, Quality of life
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|